Sharma cholinergic
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Sharma cholinergic
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Question:
Name 2 muscrainic receptors that mediate smooth muscle contraction and explain the mechanisms leading the smooth muscle contraction
Answer:
M2: inhibit AC= decrease cAMP= decrease myosin LTC kinase-P= more myosin LTC kinase active= contractionM3: activate Gq/11= activate PLC= increase in DAG+IP3= increase in IP3 mediated Ca release= contraction