Ex Phys Test 3
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Ex Phys Test 3
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Question:
What controls glycolysis? (7 things)
Answer:
o Energy charge of the cell (ATP, ADP, AMP)
§ ATP: inhibits
§ ADP and AMP: stimulates it
o Cellular redox state (NADH/NAD)
§ High amounts of NADH=high amount of energy (and large levels of citrate)
· Citric acid turns of PFK
§ In other words, build up of energy
o Entry of glucose into the muscle cell
§ GLUT4 translocation and OKINASE activity
o Enzymatic reactions: primarily PFK
o Pyruvate (PDH) complex
§ Converts pyruvate into acetyl CoA
o LDH (Lactate Dehydrogenase)
o Rate of glycogen breakdown (phosphorylase)