## Module 5

Last update by mayur on 03/31/2014
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# The Hardy-Weinberg law (equation) is a mathematical model in which allele frequencies in populations remain constant from generation to generation. Given all the conditions that must be met for the Hardy-Weinberg equation to be valid, why is this equation useful for studying population genetics?

It is useful because if a population breaks from Hardy-Weinberg, you know that one of the conditions are not being met. This is a convenient way to mathematically decide if natural selection is occurring.

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Huntington disease is caused by a single dominant gene and results in progressive mental and neurological damage. The disease is usually symptomatic when a person is between 30 and 50 years old and the patient usually dies within 15 years of diagnosis. Approximately 1 in 25,000 Caucasians have this disease. Huntington disease has not been associated with any other disease, now or in the past. Why might natural selection not have eliminated such a deleterious gene from the population?
The gene does not come into effect until after the individual reproduces, so it does not affect their reproductive fitness or ability.
Migration tends to __genetic variation between subpopulations and __ genetic variation within each subpopulation.
C, A
frequency distribution
c.phenotype proportions
normal distribution
e. bell-shaped
inbreeding coefficient
d.Probability of alleles being identical by descent
genetic drift
e. Alleles may disappear from the population simply by chance
Which of the following statistical term is a not measure of central tendency?
Correlation
Which statement is true regarding heritability and continuous variation?
A low heritability score means that genes are less influential than environment in determining phenotypic variation.
QTL mapping requires all of the following except:
a genetic map.
Flower diameter in sunflowers is a quantitative trait. A plant with 6-cm flowers, from a highly inbred strain, is crossed to a plant with 30-cm flowers, also from a highly inbred strain. The F1 have 18-cm flowers. F1 × F1 crosses yield F2 plants with flowers ranging from 6 to 30 cm in diameter, in approximately 4-cm intervals (6, 10, 14, 18, 22, 26, 30).

An 18-cm F1 plant is crossed to a 6-cm plant. What is the probability of an offspring with one additive allele, if all genes that influence this trait are unlinked?
3/8