Free Flashcard From Campbell Biology Chapter 16-17
Question:
Garrod hypothesized that "inborn errors of
metabolism" such as alkaptonuria occur because
A) genes dictate the production of specific enzymes, and
affected individuals have genetic defects that cause them to lack certain
enzymes.
B) enzymes are made of DNA, and affected individuals lack
DNA polymerase.
C) many metabolic enzymes use DNA as a cofactor, and
affected individuals have mutations that prevent their enzymes from interacting
efficiently with DNA.
D) certain metabolic reactions are carried out by ribozymes,
and affected individuals lack key splicing factors.
E) metabolic enzymes require vitamin cofactors, and affected
individuals have significant nutritional deficiencies.
Answer:
A) genes dictate the production of specific enzymes, and affected individuals have genetic defects that cause them to lack certain enzymes.